Endometriosis Testing Options
Endometriosis develops when tissue resembling the uterine lining grows in areas outside the uterus. It can cause painful periods, pelvic pain, and complications with fertility. Medical specialists perform various endometriosis tests, such as testing for BCL6, to confirm the presence of abnormal tissue growth. Here is more information about the various endometriosis testing options:
Clinical and Physical Examination
Doctors evaluate a person with endometriosis through their medical history, clinical signs and symptoms, and physical examination. To support this evaluation, clinicians document reported complaints to guide further assessment. Clinical symptoms include irregular periods, excessive bleeding, pelvic pain, pain during intercourse, and bowel or urinary symptoms. During a physical exam of the abdomen and uterus, the doctor may detect abnormalities suggestive of endometriosis
Advanced Imaging Test
Imaging used in an endometriosis test does not confirm the condition, but it can reveal cysts or identify other possible causes of symptoms. The tests involve equipment such as magnetic resonance imaging (MRI) and computed tomography (CT). MRI and CT produce detailed images of organs and tissues using magnetic fields and radio waves. Ultrasound imaging relies on high-frequency sound waves to create pictures of the reproductive organs; these images allow specialists to examine structures for abnormalities that might explain pelvic pain. Transvaginal ultrasound, performed with a probe inside the vagina, provides more detailed views of the uterus, fallopian tubes, and ovaries. This method helps distinguish between endometriosis and other conditions that may produce similar symptoms.
BCL6 Biomarker Analysis
BCL6 analysis is a specialized endometrial test used to evaluate the presence of specific biomarkers associated with endometrial dysfunction. The procedure relies on antibodies to detect BCL6 protein within the endometrial tissue. Detecting elevated BCL6 levels helps physicians identify non-receptive endometrial tissue and potential underlying reproductive issues.
The test involves examining tissue samples under controlled laboratory conditions. By analyzing BCL6 expression, doctors gain insight into factors that may affect fertility or implantation. Results from this analysis help guide clinical decisions, helping physicians determine whether further evaluation or treatment is appropriate. Each step of the process contributes to a clearer understanding of the patient’s reproductive health, supporting tailored care and management strategies.
Diagnostic Laparoscopy
Endometriosis is often evaluated through laparoscopy, a minimally invasive surgical procedure. This technique allows doctors to observe reproductive organs directly. During the procedure, several small incisions are made in the abdomen, and a thin camera is inserted to examine the pelvic area for suspected endometrial tissue.
If tissue is detected, it can sometimes be removed immediately using small instruments. For patients experiencing chronic pain or fertility concerns, removing growths during the initial procedure may help address these issues. Laparoscopy also provides a detailed view of the extent of the disease, offering higher-quality visualization than many other methods.
Surgeons may collect small tissue samples for further examination. These samples are analyzed under a microscope after being stained to assess cell types and tissue patterns. The results help confirm the presence of endometrial tissue. Along with identifying the tissue, this evaluation contributes to understanding the grade and stage of endometriosis, which informs future care and monitoring.
Genetic and Molecular Test
Gene-based tests examine patterns of gene activity linked to inflammatory pathways in individuals with endometriosis. These tests detect molecular signs of inflammation and reveal how the body responds at a cellular level. Clinicians collect samples from blood, endometrial tissue, or menstrual fluid to perform the analysis. By combining systemic and local information, these tests provide insight into genetic markers associated with the condition. When used alongside other diagnostic approaches, gene-based testing contributes to a more complete evaluation of potential endometriosis.
Protein biomarker assays measure proteins released in bodily fluids that reflect inflammation, immune activity, or abnormal cell growth. Certain biomarkers may indicate the presence of endometrial abnormalities before surgical procedures. Results from these tests help gynecologists tailor management strategies to each patient. Protein-based testing also offers additional options for early detection and can reduce the need for invasive procedures. Combining gene and protein analyses allows a broader understanding of underlying biological patterns relevant to endometriosis.
Schedule an Endometriosis Test Today
Choosing an endometriosis test allows patients to make informed decisions about their care. Testing helps clarify the diagnosis, assess the extent of the disease, and monitor how treatments are affecting symptoms. The information gained can guide daily health management and support decisions about lifestyle changes and treatment options. Schedule an appointment with a fertility expert today.
